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Since pregabalin does not pregabalin undergo significant metabolism and is excreted predominantly as unchanged drug in the urine, impaired liver function would not be expected to significantly alter pregabalin plasma concentrations .
Elderly pregabalin (>65 years) Pregabalin clearance tends to decrease with increasing age .
This decrease in pregabalin oral clearance is consistent with decreases in pregabalin creatinine clearance associated with increasing age .Tags:
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